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EXO NAD+
Korea's all-in-one plant-based exosome skin rejuvenating solution, developed by Cherry Medi. A dual-vial professional formula combining plant-derived exosomes and NAD+ with PDRN, PN, collagen, glutathione, and 8 amino acid peptides — designed for skin vitality, hydration, texture, and post-procedure recovery in professional aesthetic settings.
Skin Renewal Barrier Support NAD+ Complex PDRN 30,000 ppm Post-Procedure All-in-One
Product Overview
What Is EXO NAD+?
EXO NAD+ is Cherry Medi's flagship professional skin booster, marketed as Korea's first all-in-one skin rejuvenating solution. It runs on a dual-vial system: Vial 1 contains lyophilized plant-derived exosomes with NAD+; Vial 2 contains the PDRN + PN solvent, along with collagen, peptides, and glutathione. The two are reconstituted immediately before use to preserve exosome bioactivity.
The exosomes are extracted from the callus cultures of three botanical stem cell sources. The PDRN and PN complex is sourced from wild Alaskan salmon via a French manufacturer authorized by European health authorities, at concentrations of 30,000 ppm and 10,000 ppm respectively. Eight amino acid peptides cover specific concerns from wrinkle inhibition to pigmentation. Glutathione adds antioxidant and brightening action to the mix.
Regulatory note: EXO NAD+ is a professional aesthetic product. It is not a pharmaceutical. It has not received FDA, EMA, or equivalent drug regulatory approval. Evidence for individual actives varies — PDRN has a relatively established aesthetic medicine literature base; exosomes and NAD+ in skin contexts are still under active investigation. For professional use only.
Key Highlights
Formulation & Use-Case Focus
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Plant-Derived Exosomes — Extracted from the callus culture medium of three botanical stem cell sources. Plant-origin exosome-like nanovesicles studied for antioxidant delivery potential and biocompatibility in skin delivery contexts.
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NAD+ Complex — Nicotinamide adenine dinucleotide (NAD+) is a coenzyme involved in cellular energy metabolism, studied in skin ageing research contexts for its potential role in cellular repair and vitality.
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PDRN + PN Complex (30,000 ppm + 10,000 ppm) — High-purity polydeoxyribonucleotide and polynucleotide fraction sourced from wild Alaskan salmon, authorized by European health authorities. PDRN is one of the more evidence-established actives in the Korean aesthetic injectable category.
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Collagen + 8-Peptide Complex — Atelocollagen and hydrolyzed collagen for structural and moisture support. Eight amino acid peptides targeting distinct concerns including wrinkle inhibition, pigmentation, and elasticity.
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Glutathione Brightening — Glutathione included for antioxidant activity and brightening support within the formulation's overall skin quality focus.
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Dual-Vial Lyophilized Format — Freeze-dried exosome ampoule reconstituted with PDRN solvent immediately before use. This format preserves exosome bioactivity until the moment of application, considered the professional standard for potency maintenance in lyophilized exosome products.
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Cherry Medi, Seoul — Developed by Cherry Medi, a Seoul-based aesthetic brand within the Korean biotech professional skincare sector. Manufactured under Korean MFDS standards for professional aesthetic use.
How EXO NAD+ Fits Professional Aesthetic Practice
EXO NAD+ sits within the Korean professional skin booster category alongside HA, PDRN, and growth factor products. Its all-in-one formulation makes it a stand-alone protocol option — covering exosome signalling, DNA repair support (PDRN/PN), structural peptides, and antioxidant activity in a single reconstituted solution. It also integrates into combination protocols.
Best-Fit Use Cases
- •Post-microneedling skin renewal support
- •Skin barrier support protocols
- •Standalone exosome skin booster session
- •Vitality, radiance, and hydration focus
- •Post-laser or post-procedure recovery
Related Treatment Contexts
- •Skin rejuvenation aesthetic protocols
- •Korean skin booster workflows
- •Combination with energy-based devices
- •Regenerative aesthetics practice
- •Pigmentation and brightness-focused programs
Formulation
Active Ingredients — What's Actually in EXO NAD+
EXO NAD+ uses a dual-vial system. The actives are separated until the moment of use to maintain exosome integrity. Key components per publicly available formulation data:
Vial 1 — Lyophilized Exosome Ampoule
- •Plant-derived exosomes — extracted from three botanical stem cell callus cultures
- •NAD+ (Nicotinamide adenine dinucleotide) — cellular energy coenzyme
- •Sodium hyaluronate — humectant carrier
Vial 2 — PDRN + Collagen + Peptide Solvent
- •PDRN — 30,000 ppm, high-purity polydeoxyribonucleotide (wild Alaskan salmon origin, French manufacturer)
- •PN (Polynucleotide) — 10,000 ppm
- •Atelocollagen and hydrolyzed collagen — for structural and moisture support
- •8 amino acid peptides — covering wrinkle inhibition, pigmentation, elasticity
- •Glutathione — antioxidant and brightening function
- •Additional actives may include: tranexamic acid, ascorbic acid, arbutin, adenosine, carnitine — verify full INCI list with manufacturer documentation
Formulation note: Ingredient concentrations and full INCI list should be confirmed with manufacturer product documentation before clinical use. The above reflects publicly available formulation data. Batch-to-batch specifications may vary.
Protocol Context
How Clinicians Use EXO NAD+
Post-Microneedling Application
Applied topically immediately after microneedling while microchannels are temporarily open. The rationale for this workflow is enhanced penetration and delivery via temporary skin barrier disruption. This is an emerging professional practice — not settled clinical consensus.
Standalone Skin Booster Session
Used as a standalone injectable or topical skin booster in dedicated skin quality and vitality protocols. Its all-in-one formulation reduces the number of separate product steps required per session.
Combination with Energy-Based Devices
Pairs with laser, RF microneedling, and other energy-based device protocols. The combination of exosomes, PDRN, and peptides addresses post-treatment recovery and skin quality support simultaneously.
Recommended protocol: one set per session at 1-2 week intervals for an initial course of 3-5 treatments, with monthly maintenance sessions thereafter. Confirm protocol with manufacturer guidelines and practitioner clinical judgment.
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EXO NAD+ Questions
Most professional skin boosters target one or two active categories — HA for hydration, PDRN for tissue support, growth factors for cellular signalling. EXO NAD+ combines plant-derived exosomes, NAD+, PDRN, PN, collagen, 8 peptides, and glutathione in a single reconstituted solution. That breadth per session is what the "all-in-one" positioning describes. It does not mean the product replaces every protocol step for every indication — clinical judgment governs that.
The exosomes in EXO NAD+ are plant-derived — extracted from the callus culture medium of three botanical stem cell sources. They are plant-origin extracellular vesicle-like nanovesicles. They are not human-derived or animal-derived. The PDRN in the solvent vial is salmon DNA-derived — a separate, distinct ingredient.
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell. Research on its role in cellular energy, DNA repair, and ageing biology is active. Its inclusion in a professional skin booster reflects the trend toward pairing established regenerative actives (PDRN, peptides) with emerging ones (exosomes, NAD+) in single-protocol formulations. These are investigational applications — not established medical claims.
Yes — it is used in professional aesthetic workflows that include post-microneedling application. Its renewal and recovery support positioning fits post-procedure contexts. For practitioners focused exclusively on microneedling workflows, Exotriple also carries dedicated post-microneedling positioning within the Exosome Korea range. All microneedling exosome use is in professional and investigational contexts only.
EXO NAD+ is available for professional clinic purchase and wholesale distribution orders. Contact Exosome Korea via the Contact / Wholesale page to discuss availability, pricing, and minimum order quantities.