Human-Derived Hair & Scalp BNC Global

Hanheal Exosome Hair Filler

Human-derived exosome hair filler for professional scalp rejuvenation and mesotherapy protocols, manufactured by BNC Global Korea Ltd — the same manufacturer as Hanheal Exosome Facial Rejuvenation. A dual-component lyophilised system: 100 mg exosome powder containing human dermal fibroblast-induced multipotent cell exosomes and sodium hyaluronate, reconstituted with a 5 ml Hair Filler solvent carrying Copper Tripeptide-1, Biotinoyl Tripeptide-1, Nicotinoyl Tripeptide-1, and 10 growth factor polypeptides. Indicated for scalp, eyebrow, and eyelash alopecia protocols in professional aesthetic and mesotherapy settings.

Source Type
Human-Derived (Human Dermal Fibroblast-Induced Multipotent Cell Exosomes)
Manufacturer
BNC Global Korea Ltd (Seoul, South Korea)
Category
Hair & Scalp Care
Format
Lyophilised exosome powder (100 mg) + Hair Filler solvent (5 ml) × 5 sets per box
Key Actives
Fibroblast Exosomes + HA + Copper Tripeptide-1 + Biotinoyl Tripeptide-1 + Nicotinoyl Tripeptide-1 + 10 GF Polypeptides
Use Context
Professional Aesthetic — mesotherapy injection, clinic / practitioner use only
Scalp Alopecia Eyebrow & Eyelash Human-Derived Tripeptide Complex Dandruff & Oily Scalp BNC Global

Professional use product. No exosome products are currently FDA-approved. Claims reflect emerging scientific literature and professional use context; individual outcomes vary and are not guaranteed.

Product Overview

What Is Hanheal Exosome Hair Filler?

Hanheal Exosome Hair Filler is manufactured by BNC Global Korea Ltd, the same company that produces Hanheal Exosome Facial Rejuvenation. Both products use BNC Global's human dermal fibroblast-induced multipotent cell exosome platform — the Hair Filler is the scalp and hair iteration of the same technology, with a solvent formulation built around hair-specific peptide actives rather than the facial-grade brightening and barrier actives in the skin product.

The format is the same dual-component lyophilised system: 100 mg exosome powder reconstituted with a 5 ml active solvent, 5 sets per box. The powder contains the exosomes and sodium hyaluronate. The Hair Filler solvent carries three peptide tripeptides (Copper Tripeptide-1, Biotinoyl Tripeptide-1, Nicotinoyl Tripeptide-1) alongside 10 recombinant growth factor polypeptides covering EGF, IGF-1, bFGF, KGF, VEGF, and five further sh-polypeptides.

The solvent base is glycerin and butylene glycol-stabilised with antimicrobial support from 1,2-Hexanediol and ethylhexylglycerin.

Application areas extend beyond the scalp: Hanheal Hair Filler is indicated for eyebrow and eyelash alopecia as well as all types of scalp hair loss. This makes it one of the broader-indication hair restoration products in the range. The storage specification (1°C–30°C, no freezing required) mirrors the Hanheal facial product and is operationally convenient for clinic stock management.

Regulatory note: There are currently no FDA-approved exosome products. Hanheal Exosome Hair Filler is a professional aesthetic mesotherapy product. It is not a pharmaceutical and has not received FDA or equivalent drug approval as a treatment for alopecia or any hair loss condition. Hair and scalp claims carry the highest FDA enforcement risk. All descriptions use investigational and professional framing only. For professional use by qualified practitioners.

Manufacturer Context

BNC Global Korea — The Hanheal Platform

BNC Global Korea Ltd manufactures two products in the Exosome Korea range, both under the Hanheal brand:

Hanheal Facial Rejuvenation Hanheal Hair Filler
Exosome source Human dermal fibroblast-induced multipotent cell exosomes Human dermal fibroblast-induced multipotent cell exosomes
Powder 100 mg lyophilised × 5 100 mg lyophilised × 5
Solvent 5 ml liquid ampoule (HA, niacinamide, glutathione, copper tripeptide-1, tranexamic acid, adenosine, biotin, PN, 20+ amino acids) 5 ml Hair Filler solvent (Copper Tripeptide-1, Biotinoyl Tripeptide-1, Nicotinoyl Tripeptide-1, 10 GF polypeptides, glycerin, butylene glycol)
Target Skin rejuvenation — face Hair & scalp, eyebrows, eyelashes
Storage 1°C–30°C, no freezing 1°C–30°C, no freezing
Key Highlights

Formulation & Product Characteristics

🧬

Human Dermal Fibroblast-Induced Multipotent Cell Exosomes

The same exosome source as Hanheal Exosome Facial Rejuvenation — BNC Global's proprietary human dermal fibroblast-induced multipotent cell platform. The lyophilised powder (100 mg) contains these exosomes with sodium hyaluronate as the powder-phase carrier.

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Tripeptide Complex — Three Distinct Peptide Mechanisms

The Hair Filler solvent carries three named tripeptides working across different aspects of hair and scalp biology: Copper Tripeptide-1 (GHK-Cu) for follicular cell proliferation and ECM synthesis; Biotinoyl Tripeptide-1 (GHK-Biotin conjugate) for keratinocyte activation and hair anchoring; Nicotinoyl Tripeptide-1 (niacinamide-based) for barrier and sebum-related scalp support. This triple tripeptide combination is a distinctive feature of the Hair Filler formulation.

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10 Growth Factor Polypeptides

The solvent contains sh-Decapeptide-9, sh-Oligopeptide-1 (EGF), sh-Oligopeptide-2 (IGF-1), sh-Polypeptide-8, sh-Polypeptide-62, sh-Polypeptide-59, sh-Polypeptide-3 (KGF), sh-Polypeptide-1 (bFGF), sh-Polypeptide-9 (VEGF), sh-Polypeptide-22 — 10 recombinant growth factor polypeptides supporting the follicular microenvironment and scalp tissue quality.

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Extended Application Areas — Scalp, Eyebrows, and Eyelashes

Unlike the other scalp products in the range, Hanheal Hair Filler is explicitly indicated for eyebrow and eyelash alopecia in addition to scalp hair loss. This positions it as a broader-indication hair restoration mesotherapy product for practitioners treating facial as well as scalp alopecia.

🌡️

Storage 1°C–30°C — No Freezing Required

Like the Hanheal facial product, the Hair Filler requires no cold chain or refrigerated storage below 1°C. Store at 1°C–30°C. This is operationally convenient for clinics managing multi-product stock at room temperature. Shelf life 24 months.

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BNC Global Korea Ltd — Consistent Manufacturing Platform

Both Hanheal products use the same human dermal fibroblast-induced multipotent cell exosome platform, the same format (100 mg powder + 5 ml solvent × 5 sets), and the same storage specification. Practitioners already familiar with Hanheal Facial Rejuvenation will find the Hair Filler runs on identical clinical handling principles, with the active differentiation in the solvent.

Best-Fit Use Cases & Related Contexts

How Hanheal Hair Filler Fits Professional Practice

Hanheal Hair Filler sits at the intersection of the human-derived exosome category and the clinical mesotherapy approach to hair restoration. Its BNC Global platform credentials, broad indication scope (scalp + eyebrow + eyelash), and triple-tripeptide formulation make it well-suited to practitioners running structured mesotherapy protocols. Clinics already using Hanheal Facial Rejuvenation have a natural pathway to this product without learning a new manufacturer's handling requirements.

Best-Fit Use Cases

  • Scalp mesotherapy — all types of alopecia
  • Eyebrow alopecia restoration protocols
  • Eyelash alopecia mesotherapy
  • Dandruff, oily scalp, sensitive scalp protocols
  • Hair fragility and volume loss programmes
  • Clinics running Hanheal facial protocols (same platform)

Related Treatment Contexts

  • Korean professional mesotherapy hair workflows
  • Human-derived exosome scalp protocols
  • Comparison with Hairna (Maypharm, adipose MSC, pre-filled syringe)
  • Comparison with ASCE+ HRLV Hair (ExoCoBio, Rosa EVs)
  • Comparison with LXH / EXO ROOT (plant-based scalp range)
  • Multi-indication alopecia programmes (scalp + brows + lashes)
Formulation

Complete INCI — What's in Hanheal Exosome Hair Filler

Dual-component system. Reconstitute by adding the Hair Filler solvent (Vial 2) to the lyophilised exosome powder (Vial 1) and shaking until fully dissolved. Use immediately after reconstitution.

Vial 1 — Lyophilised Exosome Powder (100 mg)

INCI Name Common Name / ID Function
Induced Human Dermal Fibroblasts by Multipotent Cellular Exosomes Human Fibroblast MSC Exosomes Primary exosome source — BNC Global platform
Sodium Hyaluronate Hyaluronic acid Powder-phase hydration carrier

Vial 2 — Hair Filler Solvent (5 ml)

INCI Name Common Name / ID Function
WaterAquaBase carrier
Sodium ChlorideSalineIsotonic buffer
GlycerinGlycerolHumectant and solvent
Butylene GlycolBGHumectant and penetration enhancer
1,2-HexanediolAntimicrobial preservative
EthylhexylglycerinAntimicrobial preservative
Copper Tripeptide-1GHK-CuFollicular cell proliferation, ECM synthesis, hair cycle regulation
Biotinoyl Tripeptide-1GHK-BiotinKeratinocyte activation, hair anchoring, tissue recovery signalling
Nicotinoyl Tripeptide-1Niacinamide tripeptideScalp barrier, sebum regulation, anti-inflammatory
sh-Decapeptide-9Decapeptide-9Growth factor polypeptide
sh-Oligopeptide-1EGFEpidermal growth factor — cell proliferation
sh-Oligopeptide-2IGF-1Insulin-like growth factor
sh-Polypeptide-8Polypeptide-8Growth factor polypeptide
sh-Polypeptide-62Polypeptide-62Growth factor polypeptide
sh-Polypeptide-59Polypeptide-59Growth factor polypeptide
sh-Polypeptide-3KGFKeratinocyte growth factor — epidermal repair
sh-Polypeptide-1bFGFBasic fibroblast growth factor — fibroblast stimulation
sh-Polypeptide-9VEGFVascular endothelial growth factor — vascularisation
sh-Polypeptide-22Polypeptide-22Growth factor polypeptide

Formulation note: Full INCI for both components confirmed from dermafiller.shop, cross-referenced against multiple independent reseller sources. Growth factor INCI-to-common-name mapping consistent with EXOCODE and ASCE+ range verification. Full batch-specific INCI should be confirmed with BNC Global Korea Ltd manufacturer documentation before clinical use.

Protocol Context

How Clinicians Use Hanheal Exosome Hair Filler

Mesotherapy Injection — Primary Delivery

Reconstituted solution is administered intradermally by mesotherapy injection. Standard mesotherapy technique: 30G or 32G needle, intradermal depth appropriate to the treatment area. Scalp: distribute across target zones. Eyebrow / eyelash: deliver as small deposits along the treatment lines. Use immediately after reconstitution.

Hydra Stamp / Microneedling-Assisted Application

Can be administered via hydra stamp or microneedling device for topical enhanced-delivery application. The reconstituted solution is applied to the treatment area and the device is used to assist penetration. Suitable for practitioners preferring a less-invasive delivery option.

Multi-Area Protocol — Scalp, Brows, Lashes in Same Session

The broad indication scope allows practitioners to address scalp alopecia, eyebrow thinning, and eyelash loss within a single treatment course, using the same product. This positions Hanheal Hair Filler as efficient for patients presenting with diffuse hair loss affecting multiple areas simultaneously.

Recommended protocol: 3–5 sessions at 2–4 week intervals for an initial course, with maintenance sessions thereafter. Reconstitute immediately before use. Storage: 1°C–30°C; do not freeze. Shelf life 24 months. Confirm protocol with manufacturer guidelines and practitioner clinical judgment.

Specification Summary

Product Specification

Powder weight100 mg lyophilised per set
Solution volume5 ml Hair Filler solvent per set
Sets per box5 sets
Exosome sourceHuman dermal fibroblast-induced multipotent cell exosomes
Powder activesExosomes + Sodium Hyaluronate
Tripeptides (solvent)Copper Tripeptide-1 (GHK-Cu), Biotinoyl Tripeptide-1, Nicotinoyl Tripeptide-1
Growth factor polypeptides10 (EGF, IGF-1, KGF, bFGF, VEGF + 5 sh-polypeptides)
Application areasScalp, eyebrows, eyelashes
DeliveryMesotherapy injection, hydra stamp, microneedling-assisted
Storage1°C–30°C; do not freeze
Shelf life24 months
Source classificationHuman-Derived
ManufacturerBNC Global Korea Ltd (Seoul, South Korea)
BNC Global rangeHanheal (alongside Hanheal Exosome Facial Rejuvenation)
Hair & Scalp Range

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FAQ

Hanheal Exosome Hair Filler Questions

Human dermal fibroblast-induced multipotent cell exosomes — the same exosome platform BNC Global Korea uses in Hanheal Exosome Facial Rejuvenation. The powder INCI confirms: Induced Human Dermal Fibroblasts by Multipotent Cellular Exosomes. Human-derived.
Same manufacturer (BNC Global Korea), same exosome source (human dermal fibroblast-induced multipotent cell exosomes), same format (100 mg powder + 5 ml solvent × 5 sets), same storage specification (1°C–30°C). The difference is the solvent: the facial product carries niacinamide, glutathione, tranexamic acid, adenosine, and polynucleotide for skin brightening and barrier support. The hair filler solvent carries GHK-Cu, Biotinoyl Tripeptide-1, Nicotinoyl Tripeptide-1, and 10 growth factor polypeptides for scalp, eyebrow, and eyelash applications.
Yes. Hanheal Hair Filler is explicitly indicated for eyebrow and eyelash alopecia in addition to scalp hair loss, making it one of the few products in the range with a confirmed multi-area indication. Delivery to eyebrow and eyelash areas uses the same mesotherapy technique with small intradermal deposits along the treatment lines. For professional use by qualified practitioners only.
Nicotinoyl Tripeptide-1 is a niacinamide-based tripeptide. Niacinamide (Vitamin B3) has documented activity in barrier support, sebum regulation, and anti-inflammatory effects. As a tripeptide conjugate, it delivers the niacinamide mechanism with enhanced peptide-level cellular targeting. In a scalp context, it supports a balanced scalp microenvironment alongside the hair-growth-focused GHK-Cu and Biotinoyl Tripeptide-1.
Both are human-derived exosome hair products in a reconstitutable format. Hanheal Hair Filler (BNC Global) uses human dermal fibroblast-induced multipotent cell exosomes, in a dual-vial lyophilised system with a triple tripeptide + 10 GF polypeptide solvent. Hairna (Maypharm) uses adipose MSC exosomes (2xosome technology), in a 2.5 ml pre-filled ready-to-use syringe. Different exosome sources, different peptide profiles, different formats. Hanheal's multi-area indication (scalp + brows + lashes) also distinguishes it.
No. It does not carry FDA or equivalent regulatory approval as a treatment for alopecia or any hair loss condition. It is a professional aesthetic mesotherapy product for scalp and hair follicular environment support protocols. Hair and scalp claims carry the highest FDA enforcement risk. All professional communication must use investigational and professional support framing.
Hanheal Exosome Hair Filler is available for professional clinic purchase and wholesale distribution orders. Contact Exosome Korea via the Contact / Wholesale page to discuss availability, pricing, and minimum order quantities.
Hanheal Hair Filler · Clinic · Wholesale

Stock Hanheal Exosome Hair Filler

Available exclusively to verified professional clinics and wholesale partners. Contact the Exosome Korea team to discuss pricing, minimum order quantities, clinical data sheets, and protocol documentation for Hanheal Hair Filler and the full range.