Human-Derived Hair & Scalp
ASCE+ HRLV Hair
Premium human-derived exosome scalp care solution. Positioned for scalp rejuvenation and hair-loss concern contexts in professional clinic settings.
View Product Human-Derived Hair & Scalp Maypharm
Hairna Exosome Hair Filler
Human-derived exosome scalp booster for professional microneedling-assisted hair and scalp care, manufactured by Maypharm Co., Ltd (South Korea). A 2.5 ml pre-filled syringe containing adipose-derived mesenchymal stem cell exosomes isolated via Maypharm's proprietary 2xosome filtration technology, combined with Biotinoyl Tripeptide-1, Copper Tripeptide-1 (GHK-Cu), growth factors (FGF2), and supporting actives including hyaluronic acid and panthenol. Designed for scalp microneedling and mesotherapy delivery in professional clinical settings.
Professional use product. No exosome products are currently FDA-approved. Claims reflect emerging scientific literature and professional use context; individual outcomes vary and are not guaranteed.
Product Overview
What Is Hairna Exosome Hair Filler?
Hairna Exosome Hair Filler is manufactured by Maypharm Co., Ltd, a South Korean biotech company. Maypharm's exosome platform is built on human adipose-derived mesenchymal stem cells — the same cell source as ASCE+ SRLV (ExoCoBio), though Maypharm uses its own proprietary 2xosome filtration technology rather than ExoSCRT™. Note: ASCE+ HRLV Hair (also ExoCoBio) uses a different, plant-based source — Rosa Damascena Callus EVs — not adipose MSC. The 2xosome process uses tangential flow filtration to preserve exosome integrity where conventional ultracentrifugation causes particle destruction.
The format is a 2.5 ml pre-filled syringe — a single-component ready-to-use product, requiring no reconstitution. This distinguishes it from the dual-vial lyophilised format of LXH Leuco Exo Hair (CNB International) and ASCE+ HRLV Hair (ExoCoBio). The formulation combines ASC exosomes with two clinically relevant peptides: Biotinoyl Tripeptide-1 (a GHK-Biotin conjugate) and Copper Tripeptide-1 (GHK-Cu), plus FGF2 growth factor, hyaluronic acid, and panthenol.
The product is positioned for microneedling-assisted delivery or direct mesotherapy injection into the scalp. The microneedling workflow is the primary clinical application — the product is applied during or immediately after scalp microneedling to utilise the temporary channel penetration window.
Regulatory note: There are currently no FDA-approved exosome products. Hairna Exosome Hair Filler is a professional aesthetic product for scalp care protocols. It is not a pharmaceutical and has not received FDA or equivalent drug approval as a treatment for alopecia or any hair loss condition. Hair and scalp claims carry the highest FDA enforcement risk in this category. All descriptions use investigational and professional framing only. For professional use by qualified practitioners.
Formulation & Product Characteristics
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Adipose MSC Exosomes — 2xosome Filtration Technology
The exosome source is human adipose-derived mesenchymal stem cells, isolated using Maypharm's proprietary 2xosome tangential flow filtration process. Maypharm developed 2xosome specifically to address the exosome destruction associated with conventional ultracentrifugation, preserving the quality and signalling integrity of individual exosome particles.
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Biotinoyl Tripeptide-1 — GHK-Biotin Conjugate
A three-amino-acid peptide (GHK, the collagen-stimulating fragment) conjugated with Biotin (Vitamin B7). The combination targets hair follicle cell proliferation, stimulates adhesion molecule synthesis for follicle anchoring, and activates genetic expression pathways linked to tissue recovery. Efficacy comparable to minoxidil has been cited in Biotinoyl Tripeptide-1 research.
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Copper Tripeptide-1 (GHK-Cu) — Follicular Signalling
GHK-Cu is a copper-peptide complex that promotes extracellular matrix synthesis (collagen and elastin), stimulates follicular cell proliferation, and supports the hair growth cycle. Its role in follicle enlargement and hair growth cycle regulation has been observed in wound healing research. GHK-Cu also functions as an antioxidant, neutralising reactive oxygen species that damage follicle cells.
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FGF2 (Fibroblast Growth Factor 2) + Supporting Growth Factors
FGF2 (basic FGF) supports dermal papilla cell activity and scalp capillary function. The formulation also contains SCF (Stem Cell Factor) and NOG (Noggin) per multiple independent reseller sources, targeting follicular stem cell activation and Wnt pathway support.
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Hyaluronic Acid + Panthenol — Scalp Hydration Base
Sodium hyaluronate provides scalp hydration and moisture retention. Panthenol (Pro-Vitamin B5) supports scalp barrier function, soothes post-procedure sensitivity, and reduces inflammation markers — appropriate for immediate post-microneedling application.
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Pre-Filled Syringe Format — Ready-to-Use
2.5 ml pre-filled syringe. No reconstitution required — ready for direct application or injection on opening. This format differentiates Hairna from the dual-vial lyophilised systems used by LXH (CNB International) and ASCE+ HRLV Hair (ExoCoBio). Single-component format simplifies the clinical workflow for microneedling-assisted application.
Manufacturer Context
Maypharm Co., Ltd — The 2xosome Platform
Maypharm Co., Ltd is a South Korean biotech company whose exosome product range is built on the 2xosome adipose MSC exosome platform. The Hairna product family includes multiple products; the Hair Filler (2.5 ml pre-filled syringe) is the injectable/microneedling-delivery format. Maypharm also produces 2XSOME for face and neck applications using the same human stem cell exosome platform.
Maypharm's contact: maypharm@maypharm.co.kr / may-pharm.com. The Hairna product was launched in August 2023 with a formal press release positioning it as the world's first adipose stem cell exosome hair filler.
How Hairna Exosome Hair Filler Fits Professional Practice
Hairna sits at the intersection of human-derived exosome technology and microneedling-assisted scalp delivery. Its pre-filled syringe format makes it the most workflow-efficient product in the scalp range for microneedling protocols. Practitioners running scalp microneedling sessions can apply it directly without a preparation step. The human-derived source type places it alongside EXO ROOT in the regenerative medicine evidence tradition, distinct from the plant-based products (LXH Leuco Exo Hair, ASCE+ HRLV Hair).
Best-Fit Use Cases
- •Microneedling-assisted scalp exosome delivery
- •Post-scalp microneedling recovery and vitality
- •Mesotherapy intradermal scalp treatment
- •Combination with scalp LLLT or PRP
- •Follicular environment support programmes
- •Human-derived alternative to plant-based scalp options
Related Treatment Contexts
- •Korean professional scalp booster workflows
- •Microneedling scalp protocol design
- •Comparison with ASCE+ HRLV Hair (ExoCoBio)
- •Comparison with LXH Leuco Exo Hair (CNB, plant-based)
- •Trichology-adjacent professional clinic settings
- •Regenerative aesthetics — scalp and follicular focus
Formulation
Active Ingredients — What's in Hairna Exosome Hair Filler
Single-component, pre-filled 2.5 ml syringe. No reconstitution required. Key ingredients confirmed from manufacturer documentation and multiple independent reseller sources:
Core Exosome Component
- •ASC-human exosomes: Adipose-derived mesenchymal stem cell exosomes, isolated via 2xosome tangential flow filtration (Maypharm proprietary). Preserves exosome signalling integrity.
Peptide Complex
- •Biotinoyl Tripeptide-1: GHK-Biotin conjugate — promotes keratinocyte proliferation at follicle base, activates adhesion molecule synthesis, stimulates tissue recovery. Cited for hair regrowth effects comparable to minoxidil.
- •Copper Tripeptide-1 (GHK-Cu): Copper-peptide complex — extracellular matrix synthesis (collagen/elastin), follicular cell proliferation, hair growth cycle regulation, antioxidant activity.
Growth Factors
- •FGF2 (bFGF / sh-Polypeptide-1): Fibroblast Growth Factor 2 — dermal papilla cell support and scalp capillary function.
- •SCF (Stem Cell Factor): Supports follicular stem cell activation.
- •NOG (Noggin): BMP antagonist — supports Wnt pathway activity relevant to hair follicle cycling.
Supporting Actives
- •Sodium hyaluronate: Humectant — scalp hydration and moisture retention.
- •Panthenol (Pro-Vitamin B5): Scalp barrier support, anti-inflammatory, post-procedure soothing.
Formulation note: Core ingredient identities confirmed from manufacturer press release (PRNewswire, August 2023) and multiple independent reseller sources. Full INCI list and concentrations should be verified with Maypharm Co., Ltd documentation before clinical use.
How Clinicians Use Hairna Exosome Hair Filler
Microneedling-Assisted Scalp Application — Primary Protocol
The pre-filled syringe contents are applied to the scalp immediately following or during scalp microneedling (dermapen / dermaroller, 0.5–1.5 mm depth, practitioner-determined). Microneedling creates temporary micro-channels through the scalp barrier, enabling enhanced penetration of exosomes, peptides, and growth factors to the dermal layer where hair follicles are located. Apply the solution across the treated scalp zones and allow to absorb.
Mesotherapy (Intradermal Scalp Injection)
The pre-filled syringe is suitable for direct intradermal mesotherapy injection into scalp target areas. Standard mesotherapy technique: 30G or 32G needle, intradermal depth. Suitable for practitioners who prefer direct follicular-level delivery over topical microneedling application.
Combination Protocols
Compatible with LLLT (low-level laser therapy), PRP, and other scalp modalities. The human-derived exosome base, GHK-Cu, and FGF2 combination is well-suited to combination programmes addressing both follicular environment and scalp tissue quality simultaneously.
Recommended protocol: 3–6 sessions at 4–6 week intervals for an initial course, with maintenance sessions thereafter. Pre-filled syringe format allows direct clinical use without preparation time. Confirm needle gauge, injection depth, and session frequency with practitioner clinical judgment and manufacturer guidelines.
Specification Summary
Product Specification
Related Products
Explore the full Korean exosome hair and scalp care range — human-derived and plant-based.
Human-Derived Hair & Scalp
EXO ROOT
Professional two-step human-derived Korean exosome scalp rejuvenation treatment — focused on scalp balance and follicular vitality.
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Plant-Based Hair & Scalp
LXH Leuco Exo Hair
Plant-derived Korean exosome scalp vitality product for professional clinic use. Standalone scalp treatment or multi-step protocol complement.
View ProductHairna Exosome Hair Filler Questions
Human adipose-derived mesenchymal stem cells, isolated using Maypharm's proprietary 2xosome tangential flow filtration process. This is a human-derived product — not plant-based. Some resellers describe it incorrectly as plant stem cell-derived; the manufacturer's own press release (PRNewswire, August 2023) and product documentation confirm adipose MSC origin.
Different source types, manufacturers, and formats. Hairna (Maypharm) is human-derived (adipose MSC exosomes), in a pre-filled syringe with no reconstitution. LXH Leuco Exo Hair (CNB International) is plant-based (Leuconostoc + Ginseng + Camellia exosomes), in a dual-vial lyophilised format requiring reconstitution with PDRN + collagen + peptides solvent. Different evidence bases, different peptide profiles, different origin categories.
Different source type, format, and manufacturer. Hairna (Maypharm) is human-derived — adipose MSC exosomes via 2xosome TFF technology in a pre-filled 2.5 ml syringe. ASCE+ HRLV Hair (ExoCoBio) is plant-based — Rosa Damascena Callus Extracellular Vesicles (10B per vial) via ExoSCRT™ RSCE™ technology, in a lyophilised powder reconstituted with a scalp activator solution. Both are for professional scalp use; HRLV is PRP-compatible. Hairna's ready-to-use format is more workflow-efficient for microneedling sessions.
Biotinoyl Tripeptide-1 is a GHK-Biotin conjugate. GHK is a collagen-stimulating tripeptide fragment; Biotin (Vitamin B7) is essential for keratin infrastructure and scalp health. The conjugate promotes keratinocyte proliferation at the follicle base, activates adhesion molecule synthesis for follicle anchoring, and stimulates tissue recovery gene expression. Research cites efficacy comparable to minoxidil for hair regrowth in the Biotinoyl Tripeptide-1 literature.
Yes — the pre-filled syringe format supports both microneedling-assisted topical application and direct intradermal mesotherapy injection. The microneedling protocol is the primary clinical application. For direct injection, standard mesotherapy technique applies (30G/32G needle, intradermal depth). For professional use by qualified practitioners only.
No. Hairna Exosome Hair Filler does not carry FDA or equivalent regulatory approval as a treatment for alopecia or any hair loss condition. It is a professional scalp vitality product positioned for investigational aesthetic protocols. Hair and scalp claims carry the highest FDA enforcement risk. All professional communication must use investigational and supportive framing only.
Hairna Exosome Hair Filler is available for professional clinic purchase and wholesale distribution orders. Contact Exosome Korea via the Contact / Wholesale page to discuss availability, pricing, and minimum order quantities.