Selastin Exo Plus
Plant-based CICA exosome and PDRN skin rejuvenation booster, manufactured by CNB International Co., Ltd (Korea) — the same manufacturer as Exotriple, LXC Lacto Exo Colla, and LXH Leuco Exo Hair. A dual-vial lyophilised system: 100 mg Centella Asiatica Callus Extracellular Vesicle powder (with sodium hyaluronate) reconstituted with a 5 ml H-PDRN + 7-peptide active solvent containing SEATIDE (Galloy Pentapeptide-74), Nonapeptide-1, Nicotinoyl Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, ascorbic acid, atelocollagen, glutathione, carnitine, adenosine, and arginine. 5 sets per box. Skin rejuvenation, barrier repair, pore refinement, acne scar support, and brightening protocols.
No FDA-approved exosome products currently exist. Selastin Exo Plus is a professional aesthetic product — not a pharmaceutical. For professional use by qualified practitioners only. This product is skin-only.
What Is Selastin Exo Plus?
Selastin Exo Plus is manufactured by CNB International Co., Ltd, the same Korean company responsible for Exotriple (Riola brand), LXC Lacto Exo Colla, and LXH Leuco Exo Hair on this site. Selastin is CNB's skin booster brand line, distinct from the Riola brand used for Exotriple. This makes CNB International the most represented manufacturer in the range: four products from the same Korean company, each targeting a different clinical positioning.
Selastin Exo Plus uses the same Centella Asiatica Callus Extracellular Vesicle (CICA exosome) source as Exotriple — confirming this is a core CNB International exosome platform. Where Exotriple is positioned primarily for post-microneedling skin rejuvenation, Selastin Exo Plus has a broader skin concern profile: acne and scar repair, barrier restoration, redness and irritation, brightening, and pore refinement alongside the core collagen stimulation and rejuvenation positioning.
The formulation architecture is CNB International's standard dual-vial system: lyophilised CICA exosome powder + active solvent. The Selastin Exo Plus solvent is significantly more complex than Exotriple's solvent — 7 named peptides versus Exotriple's simpler PDRN carrier, adding SEATIDE (Galloy Pentapeptide-74, a seaweed-derived peptide), Nonapeptide-1, Nicotinoyl Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, and Palmitoyl Tetrapeptide-7 alongside ascorbic acid, atelocollagen, glutathione, carnitine, and adenosine.
Regulatory note: There are currently no FDA-approved exosome products. Selastin Exo Plus is a professional aesthetic product. It is not a pharmaceutical. For professional use by qualified practitioners only. Hair and scalp claims carry the highest FDA enforcement risk — this product is skin-only.
CNB International — The Full Site Range
CNB International Co., Ltd is the manufacturer with the broadest product presence on this site. All four products use CNB's consistent dual-vial lyophilised format with H-PDRN as a solvent backbone:
Formulation & Product Characteristics
Centella Asiatica Callus Extracellular Vesicles — CICA Exosome
The exosome source is Centella Asiatica (tiger grass) callus culture — the same CICA exosome source CNB International uses in Exotriple. Centella Asiatica is one of the most studied botanicals in Korean skincare for its soothing, barrier-repair, and wound-healing properties. The callus-derived exosomes carry the signalling payload of Centella at a cellular delivery level.
SEATIDE (Galloy Pentapeptide-74) — Seaweed-Derived Peptide
Galloy Pentapeptide-74, marketed as SEATIDE, is a seaweed-derived bioactive pentapeptide. It supports skin barrier repair, anti-inflammatory activity, and cellular regeneration. It is relatively uncommon in Korean skin booster formulations — its presence distinguishes Selastin Exo Plus's peptide complex from the more standard sh-oligopeptide growth factor profiles used in other products in the range.
H-PDRN — High-Purity PDRN (CNB International Specification)
H-PDRN denotes CNB International's high-purity polydeoxyribonucleotide specification — the same quality designation used in Exotriple and LXC Lacto Exo Colla (wild Alaskan salmon, French manufacturer, European health authority authorised). PDRN activates A2A adenosine receptors on fibroblasts, promoting collagen synthesis, tissue repair, and anti-inflammatory activity.
7-Peptide Complex in the Solvent
Galloy Pentapeptide-74 (SEATIDE), Nonapeptide-1, Nicotinoyl Tripeptide-1, Acetyl Hexapeptide-8 (neuromodulating), Palmitoyl Pentapeptide-4 (Matrixyl, collagen synthesis), Palmitoyl Tetrapeptide-7 (anti-inflammatory), and an implied peptide from atelocollagen. These 7 peptides target a broader range of skin repair, barrier, and anti-ageing mechanisms than the more growth-factor-focused peptide profiles in other products.
Brightening + Antioxidant Layer: Ascorbic Acid + Glutathione
Ascorbic acid (Vitamin C) and glutathione in the same formulation. Ascorbic acid inhibits melanin synthesis directly; glutathione provides systemic antioxidant protection and contributes to skin brightening through the glutathione-melanin competitive pathway. Both are established brightening actives in Korean professional aesthetic formulations.
Atelocollagen + Carnitine + Adenosine
Atelocollagen for structural ECM support (same as Exotriple). Carnitine for cellular energy metabolism and fat metabolism support at the skin level. Adenosine for anti-wrinkle and skin vitality support — an established Korean cosmetics active with documented wound healing and anti-ageing effects.
How Selastin Exo Plus Fits Professional Practice
Selastin Exo Plus is the most multi-indication plant-based skin booster in the CNB International range. Where Exotriple's primary positioning is post-microneedling rejuvenation, Selastin Exo Plus extends into acne and scar repair, barrier restoration, redness management, and brightening. The broader peptide complex and the SEATIDE + CICA combination make it well-suited to reactive, sensitive, post-acne, and barrier-compromised skin presentations alongside general rejuvenation.
Best-Fit Use Cases
- •Skin rejuvenation — general quality and radiance
- •Acne scar repair and post-inflammatory support
- •Redness, irritation, and sensitive skin protocols
- •Post-procedure barrier recovery (laser, peel)
- •Brightening and uneven tone programmes
- •Pore refinement and texture improvement
Related Treatment Contexts
- •CNB International exosome skin booster workflows
- •Comparison with Exotriple (same CICA exosome, simpler solvent)
- •Comparison with LXC Lacto Exo Colla (triple exosome, same manufacturer)
- •Post-laser / post-peel professional aftercare
- •Sensitive or reactive skin MTS protocols
- •Combination with PDRN mesotherapy programmes
Complete INCI — What's Actually in Selastin Exo Plus
Selastin Exo Plus uses CNB International's standard dual-vial lyophilised reconstitution system. Pour Ampoule 2 (PDRN + Peptide solvent) into Ampoule 1 (CICA exosome powder) and shake 3–4 times until fully dissolved. Apply immediately.
Ampoule 1 — CICA Exosome Powder (100 mg)
Ampoule 2 — H-PDRN + 7-Peptide Solvent (5 ml)
Formulation note: Full INCI for both ampoules confirmed from cosmetix.eu (EU reseller) cross-referenced against premiumdermalmart.com and multiple independent sources. CNB International manufacturer confirmation via the EC21 platform listing. Full batch-specific INCI should be confirmed with CNB International Co., Ltd before clinical use.
How Clinicians Use Selastin Exo Plus
MTS (Micro-Needle Therapy System) — Primary Protocol
Apply reconstituted solution to clean skin, wait 1–3 minutes for initial absorption, then apply again and use MTS device. Standard MTS protocol: this is CNB International's recommended delivery method, consistent with Exotriple and LXC Lacto Exo Colla. Treatment interval: every 2 weeks.
Mesotherapy Injection
Administer as intradermal mesotherapy injection for direct dermal delivery. Standard mesotherapy technique. Suitable for face, neck, décolleté, and body areas.
Post-Laser / Post-Peel & Acne Scar Repair
The CICA exosome + PDRN combination with barrier-repair actives (SEATIDE, atelocollagen, adenosine) makes Selastin Exo Plus well-positioned for post-procedure recovery. Anti-inflammatory actives (CICA, Palmitoyl Tetrapeptide-7, adenosine), regenerative actives (PDRN, exosomes), and brightening support (ascorbic acid, glutathione, Nonapeptide-1) make it suited to acne-prone and post-inflammatory presentations. Not for use on actively wounded, eczema, or dermatitis skin.
Recommended protocol: 3–6 sessions spaced 2–4 weeks apart. One set (100 mg powder + 5 ml solvent) per session. Reconstitute immediately before use. Use immediately after reconstitution. Do not apply to wounded skin, active eczema, or dermatitis. Store unopened at 2–8°C.