Exovera 3X
Plant-based triple exosome skin rejuvenation booster, manufactured by Hucosmedic (South Korea). A dual-vial lyophilised system: 100 mg exosome powder containing three exosome sources — Lactobacillus (fermented bacteria), Ginseng Callus, and Centella Asiatica Callus — reconstituted with a 6 ml Repair Solution containing Sodium DNA (PDRN), Atelocollagen, Hydrolyzed Collagen, Tranexamic Acid, 7 types of peptides, and Glutathione. 5 sets per box. The '3X' name refers to the three distinct exosome sources. Positioned for skin rejuvenation, brightening, and barrier repair.
No FDA-approved exosome products currently exist. Exovera 3X is a professional aesthetic product — not a pharmaceutical. For professional use by qualified practitioners only.
What Is Exovera 3X?
Exovera 3X is manufactured by Hucosmedic, a South Korean aesthetic product company. The Exovera brand covers multiple product types including Exovera 3X (this product), the Exovera Ultra-Soothing Barrier Support Cream, and the Exovera 3X Exosome Soothing Mask — all built around the CICA exosome theme. Exovera 3X is the injectable/MTS professional skin booster in the range.
The '3X' designation refers to the three distinct exosome sources in the lyophilised powder: Lactobacillus (fermented bacteria, probiotic/microbiome-supportive vesicles), Ginseng Callus (Panax ginseng stem cell culture, phyto-growth factors), and Centella Asiatica Callus (CICA, soothing and barrier repair). This triple fermented-plant-botanical combination has a direct parallel with CNB International's LXC Lacto Exo Colla, which uses the same three source types (Lactobacillus + Ginseng + CICA). Exovera 3X is a different manufacturer (Hucosmedic, not CNB International) with a different repair solution composition.
The Repair Solution is where Exovera 3X distinguishes itself from LXC: it includes Tranexamic Acid as a brightening active alongside the PDRN, atelocollagen, hydrolyzed collagen, 7 peptides, and glutathione. Tranexamic acid's melanin pathway inhibition mechanism adds a brightening and tone-correction dimension that LXC's solvent does not carry.
Regulatory note: There are currently no FDA-approved exosome products. Exovera 3X is a professional aesthetic product. It is not a pharmaceutical. For professional use by qualified practitioners only.
Formulation & Product Characteristics
Triple Exosome Complex — Lacto + Ginseng + CICA
Three distinct plant and fermentation-derived exosome sources working in combination. Lactobacillus vesicles bring probiotic/microbiome-supportive properties. Ginseng Callus EVs contribute phyto-growth factors and regenerative antioxidant activity. Centella Asiatica Callus EVs (CICA) provide the barrier-repair and anti-inflammatory payload. The three-source approach delivers a broader molecular signalling profile than single-source exosome products.
Tranexamic Acid in the Repair Solution
Tranexamic acid competitively inhibits plasminogen binding to keratinocytes, reducing UV-induced prostaglandin release that stimulates melanocyte activation. It is one of the better-documented topical brightening actives in Korean professional aesthetics. Its inclusion in the Repair Solution gives Exovera 3X a brightening/tone-correction dimension not present in most PDRN + exosome combination products in the range.
PDRN (Sodium DNA) + Dual Collagen Complex
Sodium DNA is the INCI name for PDRN (polydeoxyribonucleotide). Paired with both Atelocollagen and Hydrolyzed Collagen in the same solvent for dual structural ECM support — intact atelocollagen for fibrillar matrix support, and hydrolyzed collagen for moisture retention and skin-available collagen peptides.
7 Types of Peptides + Glutathione
Seven peptides in the Repair Solution covering distinct skin quality targets (specific identities to confirm with Hucosmedic manufacturer documentation). Glutathione provides antioxidant protection and brightening support as a tripeptide antioxidant.
100 mg Powder + 6 ml Repair Solution — Larger Format
At 100 mg powder + 6 ml solution per set, Exovera 3X uses a larger volume than many comparable products in the range (most use 100 mg + 5 ml). The 6 ml Repair Solution volume provides more reconstituted solution per session.
Hucosmedic, South Korea
Manufacturer of the Exovera brand. Hucosmedic also produces the Exovera Ultra-Soothing Barrier Support Cream (CICA exosome 50,000 ppm topical cream) and the Exovera 3X Soothing Mask. Hucosmedic's approach uses the three-source triple exosome architecture.
Exovera 3X vs LXC Lacto Exo Colla
Two products in the site range use the same triple exosome combination (Lactobacillus + Ginseng + CICA). The differences lie in manufacturer, powder weight, solvent composition, and solvent volume:
How Exovera 3X Fits Professional Practice
Exovera 3X is broadly positioned across skin rejuvenation, with a particular brightening/tone angle from Tranexamic Acid. The triple exosome complex covers inflammation, microbiome/probiotic support, and regenerative signalling simultaneously. Its 6 ml solution volume gives slightly more reconstituted product per session than comparable products.
Best-Fit Use Cases
- •Skin rejuvenation and overall quality improvement
- •Brightening and uneven tone protocols
- •Barrier repair and sensitive skin
- •Post-procedure recovery (laser, peel, microneedling)
- •Acne and post-inflammatory presentations
- •Multi-benefit protocol — single product covering multiple concerns
Related Treatment Contexts
- •Comparison with LXC Lacto Exo Colla (same exosome types, CNB International)
- •Comparison with Selastin Exo Plus (CICA, different manufacturer)
- •Comparison with EXOCODE Radiance-R (tone focus, plant EVs, topical)
- •Post-laser tone and repair combined protocols
- •Korean triple exosome professional workflows
- •Combination with energy-based devices or MTS
Complete INCI — What's in Exovera 3X
Dual-vial system. Add the Repair Solution (Ampoule 2) to the exosome powder (Ampoule 1) and shake until fully dissolved. Use immediately.
Ampoule 1 — Triple Exosome Powder (100 mg)
Ampoule 2 — Repair Solution (6 ml)
Formulation note: Triple exosome sources, Repair Solution active categories, and the tranexamic acid inclusion confirmed from lgcaesthetic.com, derma-solution.com, cosmetix.eu, and skin-reboot.com. Specific peptide INCI identities not disclosed in publicly available documentation — confirm with Hucosmedic manufacturer documentation before clinical use.
How Clinicians Use Exovera 3X
Mesotherapy Injection
Intradermal mesotherapy injection across the treatment area. Standard mesotherapy technique, 30G or 32G needle. Face, neck, décolleté.
MTS / Microneedling Application
Apply to skin after MTS or microneedling while microchannels are open, or use the MTS device to drive the solution into the dermis. One set per session.
Post-Procedure Brightening + Repair
The CICA exosome + PDRN + Tranexamic Acid combination makes Exovera 3X suited for post-laser or post-peel sessions where both repair and brightening/tone management are indicated simultaneously.
Recommended protocol: 3–6 sessions at 2–4 week intervals. Reconstitute immediately before use. Use immediately after reconstitution. Store unopened at 2–8°C.