Dermaheal HL
Professional mesotherapy cocktail for scalp vitality and hair care, manufactured by Caregen Co., Ltd (Seoul, South Korea). A ready-to-use 5 ml solution containing 56 active ingredients: 4 Caregen-proprietary biomimetic peptides (Decapeptide-4, Acetyl Decapeptide-3, Oligopeptide-41, Copper Tripeptide-1), 3 recombinant growth factors (IGF-1, bFGF, VEGF), 13 vitamins, 24 amino acids, 5 minerals, 4 coenzymes, 4 nucleic acids, and 2 reducing agents. Not an exosome product — a biomimetic peptide and growth factor mesotherapy cocktail from one of Korea's leading peptide biotechnology companies. 10 vials per box; one vial per session.
Product category note: Dermaheal HL is a biomimetic peptide and growth factor mesotherapy cocktail. It does not contain exosomes. This distinguishes it from all other hair products on this site. It is included because it is a clinically established, widely used professional scalp mesotherapy preparation that complements exosome-based scalp protocols in the same treatment programmes.
Professional use product. Dermaheal HL contains no exosomes. Not FDA-approved as a hair loss treatment. Claims reflect professional use context and established practitioner track record. Individual outcomes vary and are not guaranteed.
What Is Dermaheal HL?
Dermaheal HL is a professional scalp mesotherapy cocktail manufactured by Caregen Co., Ltd, a Korean biotech company that has spent over a decade researching biomimetic peptides and growth factors. Caregen is the manufacturer of the Dermaheal brand, which covers a range of professional mesotherapy products for skin, scalp, and body.
Unlike every other hair product on this site, Dermaheal HL contains no exosomes. It is a synthetic biomimetic peptide and growth factor cocktail — a different technology category. Caregen's approach is to produce proprietary biomimetic peptides that mimic the signalling activity of naturally occurring growth factors, combined with a comprehensive micronutrient matrix covering vitamins, amino acids, minerals, coenzymes, and nucleic acids that the scalp and hair follicle need as building blocks for healthy function.
The formulation uses Caregen's double-layered encapsulation technology, which encapsulates the active molecules in a two-layer structure that improves penetration past the stratum corneum and protects the actives from degradation by endogenous proteases. This allows the biomimetic peptides and growth factors to reach their target cells — fibroblasts, hair follicle cells, and scalp vasculature — at effective concentrations.
Dermaheal HL is one of the most widely used professional scalp mesotherapy cocktails internationally, with a substantial practitioner track record that predates the exosome era. It is commonly used alongside exosome-based scalp products as part of combination protocols.
Regulatory note: There are currently no FDA-approved exosome products; Dermaheal HL contains no exosomes and is not in that category. It is a professional aesthetic cosmeceutical mesotherapy product. It is not a pharmaceutical and has not received FDA or equivalent drug approval as a treatment for alopecia or any hair loss condition. Hair and scalp claims carry the highest FDA enforcement risk. All descriptions use investigational and professional framing only. For professional use by qualified practitioners.
Biomimetic Peptides vs Exosomes — Where Dermaheal HL Fits
Dermaheal HL represents an older and more established strand of Korean professional aesthetic biotechnology than the exosome products in this range. The distinction is worth being explicit about for practitioners:
Formulation & Product Characteristics
4 Caregen-Proprietary Biomimetic Peptides
Decapeptide-4 (CG-IDP2), Acetyl Decapeptide-3 (Rejuline), Oligopeptide-41 (CG-Keramin1), and Copper Tripeptide-1 (CG-Copper Peptide). Each addresses a specific aspect of follicular biology: collagen/elastin synthesis and hair shaft strength, hair cell regeneration, hair cell proliferation and migration, and follicular circulation and ECM support. All are Caregen proprietary INCI designations.
3 Growth Factors — Caregen BIO-Placenta Complex
sh-Oligopeptide-2 (CG-IGF1 / IGF-1), sh-Polypeptide-1 (CG-bFGF / bFGF), sh-Polypeptide-9 (CG-VEGF / VEGF). These three growth factors form Caregen's BIO-Placenta complex. IGF-1 and bFGF support cell proliferation and fibroblast activity; VEGF stimulates scalp angiogenesis and improves capillary blood supply to hair follicles.
56 Active Ingredients Total — Comprehensive Scalp Nutritional Matrix
13 vitamins (A, B1, B2, B3, B5, B6, B7, B9, B10/PABA, B12, E, K, inositol), 24 amino acids, 5 minerals, 4 coenzymes, 4 nucleic acids, 2 reducing agents. This matrix provides the full spectrum of micronutrients required for hair follicle cell metabolism, keratin synthesis, and scalp tissue maintenance.
Double-Layered Encapsulation Technology
Caregen's proprietary encapsulation wraps active molecules in a two-layer structure that improves penetration through the stratum corneum and protects biomimetic peptides and growth factors from degradation by endogenous proteases. This is a key differentiator in how Dermaheal products achieve delivery to target cells compared to non-encapsulated mesotherapy cocktails.
Caregen Co., Ltd — 13+ Years of Peptide R&D
Caregen has been developing growth factors and biomimetic peptides for cosmeceutical and pharmaceutical applications since 2008. Dermaheal is their established professional brand. The Dermaheal HL formulation is one of the most widely used professional scalp mesotherapy products internationally.
Alcohol-Free, Fragrance-Free
Confirmed from INCIDecoder analysis. Suitable for sensitive scalp presentations. No preservative alcohol systems that could irritate the treated scalp.
The 4 Caregen Peptides — What Each One Does
The four biomimetic peptides are the primary differentiators of Dermaheal HL from generic vitamin mesotherapy cocktails. Each has a distinct mechanism:
How Dermaheal HL Fits Professional Aesthetic Practice
Dermaheal HL occupies a different position from the exosome products in this range — it is the scalp nutritional and peptide-signalling baseline rather than the cellular communication vehicle. Many practitioners run it as the primary scalp restoration protocol, with exosome products added in as combination or intensification steps. Its 56-ingredient matrix ensures the scalp has the full micronutrient substrate for follicular activity; the biomimetic peptides and growth factors drive the signalling directly.
Best-Fit Use Cases
- •Standalone scalp mesotherapy protocol
- •Baseline scalp nutrition programme
- •Androgenetic alopecia mesotherapy
- •Diffuse thinning and reduced hair density
- •Seborrhea, dandruff, oily scalp support
- •Combination with exosome scalp products
Related Treatment Contexts
- •Caregen / Dermaheal brand mesotherapy workflows
- •Scalp mesotherapy preceding exosome product introduction
- •Combination with PRP for enhanced growth factor delivery
- •Combination with LLLT or energy-based scalp devices
- •Practitioners transitioning from PDRN to biomimetic peptide protocols
- •Trichology and dermatology adjacent clinic settings
56 Active Ingredients — Breakdown
Biomimetic Peptides (4)
Decapeptide-4 (CG-IDP2), Acetyl Decapeptide-3 (Rejuline), Oligopeptide-41 (CG-Keramin1), Copper Tripeptide-1 (GHK-Cu)
Growth Factors (3) — Caregen BIO-Placenta Complex
sh-Oligopeptide-2 / IGF-1 (CG-IGF1), sh-Polypeptide-1 / bFGF (CG-bFGF), sh-Polypeptide-9 / VEGF (CG-VEGF)
Vitamins (13)
Retinol (A), Thiamine Nitrate (B1), Riboflavin (B2), Niacinamide (B3), Calcium Pantothenate (B5), Pyridoxine (B6), Biotin (B7), Folic Acid (B9), Aminobenzoic Acid / PABA (B10), Cyanocobalamin (B12), Inositol, Tocopherol (E), Menadione (K)
Amino Acids (24)
Full essential and non-essential amino acid profile covering 24 amino acids. Specific identities to confirm with Caregen product documentation — include the complete list of building blocks for keratin, collagen, and scalp tissue proteins.
Minerals (5), Coenzymes (4), Nucleic Acids (4), Reducing Agents (2)
Mineral panel providing essential cofactors for enzymatic scalp cell activity. Coenzymes supporting cellular energy and metabolic reactions. Nucleic acid precursors supporting cell division and hair follicle regeneration. Two reducing agents providing antioxidant protection.
Formulation note: Biomimetic peptides, growth factors, and vitamin identities confirmed from multiple independent reseller sources including topdermal.com, okdermo.com, derma-solution.com, and prpmed.de. Full INCI should be confirmed with Caregen Co., Ltd manufacturer documentation before clinical use. Minor reseller-to-reseller variation in total counts (13 vs 14 vitamins; 3 vs 4 vs 5 minerals) reflects different batch/version documentation; the figures used here reflect the most consistent values across authoritative sources.
How Clinicians Use Dermaheal HL
Mesotherapy Injection — Primary Delivery
Standard scalp mesotherapy technique: intradermal injection into the scalp using 30G or 32G needle. Apply across treatment zones: diffuse thinning areas, recession lines, or targeted loss zones. One 5 ml vial per session. The double-layered encapsulation enhances delivery and bioavailability to follicular target cells.
Microneedling-Assisted Topical Application
Applied topically during or immediately after scalp microneedling while microchannels are open. The encapsulated actives penetrate the scalp dermis via the temporary barrier disruption. The 56-ingredient matrix delivers broad nutritional support to the follicular environment in each session.
Combination with Exosome Scalp Products
Dermaheal HL is widely used in combination with exosome-based scalp products in the same session or alternating sessions. The peptide/growth factor/nutritional matrix of Dermaheal HL and the cellular signalling payload of exosome products (ASCE+ HRLV, LXH, EXO ROOT, Hairna) are complementary rather than competitive. The combination provides both direct signalling and the micronutrient substrate for follicular response.
Combination with PRP
Compatible with PRP combination protocols. The platelet-derived growth factors in PRP complement Caregen's BIO-Placenta growth factor complex. Combined in the same session or as alternating treatments within a structured scalp programme.
Standard protocol: 1 session per week, course of 10 sessions (one full box). Results typically become visible at 2–5 months into the course. One 5 ml vial per session. Confirm protocol frequency and total session count with practitioner clinical judgment and Caregen product guidelines.